The data foundation for life science AI

From literature to label.
In one API.

Publications, genes, molecules, clinical trials, patents, and the full FDA & EMA record — one cross-linked Core graph your models and agents query through a single API.

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Click a core for its data at a glance — coverage, breakdowns, and the fields you can filter on

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What goes into the Cores

Dozens of upstream feeds, from public registries and agency records to curated reference databases and the patent offices, land behind one schema on a continuous ingest cadence.

BiomedCore

Publications

PubMed citations, abstracts and MeSH indexing
PubMed Central open-access full text
Crossref DOI, journal and publisher metadata
Reference lists and forward citations
NLM journal catalogue and ISSN registry
Retraction, correction and erratum notices
Databank accessions cited on the record: registries, sequences, structures

GeneCore

Genes & targets

HGNC approved symbols, aliases and previous names
Ensembl gene models, biotype and genomic location
NCBI Gene and RefSeq curated summaries
UniProt Swiss-Prot function, disease and family annotation
Gene Ontology terms and Reactome pathway membership
Target class, tractability buckets and chemical probes
gnomAD constraint, essentiality screens and safety liabilities

DrugCore

Molecules

ChEMBL molecule registry: structures, InChI and SMILES
GSRS substance records from FDA, NCATS, EMA and USP
INN, USAN, ATC and UNII identifiers
Trade names and full synonym sets
Mechanism of action and target assignments
Parent, salt-form and prodrug relationships
Modality and highest clinical stage reached

TrialCore

Clinical trials

ClinicalTrials.gov study records, via the CTTI AACT release
WHO ICTRP national registries: CTIS, EudraCT, ISRCTN, jRCT, ChiCTR, CTRI, ANZCTR, DRKS and more
Sponsors, collaborators and cooperative groups
Conditions, interventions and MeSH browse terms
Design, arms, eligibility criteria and enrolment
Reported outcomes, result groups and measurements
Protocol identifiers and linked publications

RegulatoryCore

FDA + EMA

Drugs@FDA applications, approval status and dates
FDA product labels, parsed section by section
FDA review packages: medical, clinical pharmacology, statistical
Orphan Drug Product designations
Expedited programs: breakthrough, fast track, priority review, accelerated approval
Withdrawal notices from the Federal Register and 21 CFR 216.24
EMA European public assessment reports (EPARs)
EMA Summary of Product Characteristics, Annex I
openFDA marketing status and product listings

PatentCore

Preview

Patents

USPTO, EPO and WIPO publications: grants and applications
Full text: title, abstract, claims and description
CPC and IPC classifications
Assignees, inventors, priority and grant dates
DOCDB simple patent families
SureChEMBL compounds annotated from patent text
Patent-to-patent and patent-to-literature citations

One query, every source. Ask the Core, not the upstream. The answer arrives in the same shape whichever feed it came from.

Find work by the two scientists most central to GLP-1 biology: Lotte Bjerre Knudsen (Novo Nordisk, designed semaglutide) and Daniel Drucker (Toronto, discovered GLP-1's incretin effect).

queryGLP-1 receptor agonist obesityincludeauthorsMetadataminPublicationDate2018-01-01authorNamesLotte Bjerre KnudsenDaniel Drucker

Request

GET https://api.amass.tech/api/v1/cores/biomedcore/records?query=GLP-1%20receptor%20agonist%20obesity&include=authorsMetadata&minPublicationDate=2018-01-01&authorNames=Lotte%20Bjerre%20Knudsen&authorNames=Daniel%20Drucker

Response · 200 OK

{
  "data": [
    {
      "amassId": "AMBC_RwzeOtqYiRA2S523v1jL81OgndQ",
      "pmid": "34626851",
      "pmcid": "PMC8859548",
      "doi": "10.1016/j.molmet.2021.101351",
      "title": "GLP-1 physiology informs the pharmacotherapy of obesity",
      "abstract": "BACKGROUND: 
Glucagon-like peptide-1 receptor agonists (GLP1RA) augment glucose-dependent insulin release and reduce glucagon secretion and gastric emptying, enabling their successful development for the treatment of type 2 diabetes (T2D).…",
      "authors": ["Daniel J. Drucker"],
      "journal": "Molecular metabolism",
      "issn": "2212-8778",
      "volumeIssue": "57",
      "language": "eng",
      "publicationDate": "2022-03-01",
      "publicationTypes": ["Journal Article", "Research Support, Non-U.S. Gov't", "Review"],
      "isRetracted": false,
      "citationCount": 423,
      "journalQualityJufo": 2,
      "meshTerms": ["Adolescent", "Animals", "Diabetes Mellitus, Type 2", "Glucagon-Like Peptide 1", "Glucagon-Like Peptide-1 Receptor", …],
      "keywords": ["Brain", "Diabetes", "G protein-coupled receptor", "Hunger", "Obesity", …],
      "substances": ["Glucagon-Like Peptide-1 Receptor", "Liraglutide", "Glucagon-Like Peptide 1"],
      "hasFulltext": false,
      "authorsMetadata": [
        {
          "name": "Daniel J. Drucker",
          "orcid": "0000-0001-6688-8127",
          "affiliations": [{ "name": "Lunenfeld-Tanenbaum Research Institute", "ror": "01s5axj25", "countryCode": "CA" }]
        }
      ],
      "meshIds": ["D000293", "D000818", "D003924", "D052216", "D000067757", …],
      "substanceIds": ["D000067757", "D000069450", "D052216"],
      "referencesTrialCore": [],
      "references": ["AMBC_5km7Q541cJN5a8RcTUN2tcgYoRj", "AMBC_WUubCFjk6wfURImFXwtDEvKquIE", "AMBC_3pwzL1urfguQm7s2L8Jlj04onOR", "AMBC_YDNDzsaB3vLPfxW6MNxdJU7vwI0", "AMBC_KH7wBl2Araj9gbLXuQWOHefvkIs", …],
      "citedBy": ["AMBC_B5CfpHBkdFha6MX0Q2GJpCBMw3o", "AMBC_UAflDqTKZtUAEny8XTtIvPvCWu7", "AMBC_P2sn7qrFvXfd8grl0s5scQ2El3t", "AMBC_5Er4ez0MRO1LsHzGpqflcUlzSFZ", "AMBC_PB5LfnIhIOOXiZLcXAokubVODU8", …]
    },
    { "pmid": "32987188", "title": "Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease", "citationCount": 270, … },
    { "pmid": "35907261", "title": "Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease", "citationCount": 113, … },
    { "pmid": "41654015", "title": "Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues", "citationCount": 0, … },
    { "pmid": "29317623", "title": "GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose", "citationCount": 181, … }
  ]
}

40M+

Publications

43K+

Genes & targets

22K+

Molecules

1.2M+

Clinical trials

7K+

FDA + EMA authorizations

16M+

Patents

Cross-linked by design. Follow any paper to its targets, any target to its molecules, any molecule to its trials, and any trial back to the evidence.

Click any core in the graph above to see what's inside.

Build with the Amass *Cores

Get started

From API key to first response in minutes. Auth, requests, and parsing your first result.

Built for AI agents

A one-page reference your LLM can read top to bottom — drop it into a prompt and call the API.

Example workflows

End-to-end queries for literature review, pipeline tracking, and trial intelligence.

From literature to label.
In one API.

Publications, genes, molecules, clinical trials, patents, and the full FDA & EMA record — one cross-linked Core graph your models and agents query through a single API.

live linkplanned

Click a core for its data at a glance — coverage, breakdowns, and the fields you can filter on

What goes into the Cores

Dozens of upstream feeds, from public registries and agency records to curated reference databases and the patent offices, land behind one schema on a continuous ingest cadence.

BiomedCore

Publications

PubMed citations, abstracts and MeSH indexing
PubMed Central open-access full text
Crossref DOI, journal and publisher metadata
Reference lists and forward citations
NLM journal catalogue and ISSN registry
Retraction, correction and erratum notices
Databank accessions cited on the record: registries, sequences, structures

GeneCore

Genes & targets

HGNC approved symbols, aliases and previous names
Ensembl gene models, biotype and genomic location
NCBI Gene and RefSeq curated summaries
UniProt Swiss-Prot function, disease and family annotation
Gene Ontology terms and Reactome pathway membership
Target class, tractability buckets and chemical probes
gnomAD constraint, essentiality screens and safety liabilities

DrugCore

Molecules

ChEMBL molecule registry: structures, InChI and SMILES
GSRS substance records from FDA, NCATS, EMA and USP
INN, USAN, ATC and UNII identifiers
Trade names and full synonym sets
Mechanism of action and target assignments
Parent, salt-form and prodrug relationships
Modality and highest clinical stage reached

TrialCore

Clinical trials

ClinicalTrials.gov study records, via the CTTI AACT release
WHO ICTRP national registries: CTIS, EudraCT, ISRCTN, jRCT, ChiCTR, CTRI, ANZCTR, DRKS and more
Sponsors, collaborators and cooperative groups
Conditions, interventions and MeSH browse terms
Design, arms, eligibility criteria and enrolment
Reported outcomes, result groups and measurements
Protocol identifiers and linked publications

RegulatoryCore

FDA + EMA

Drugs@FDA applications, approval status and dates
FDA product labels, parsed section by section
FDA review packages: medical, clinical pharmacology, statistical
Orphan Drug Product designations
Expedited programs: breakthrough, fast track, priority review, accelerated approval
Withdrawal notices from the Federal Register and 21 CFR 216.24
EMA European public assessment reports (EPARs)
EMA Summary of Product Characteristics, Annex I
openFDA marketing status and product listings

PatentCore

Preview

Patents

USPTO, EPO and WIPO publications: grants and applications
Full text: title, abstract, claims and description
CPC and IPC classifications
Assignees, inventors, priority and grant dates
DOCDB simple patent families
SureChEMBL compounds annotated from patent text
Patent-to-patent and patent-to-literature citations

One query, every source. Ask the Core, not the upstream. The answer arrives in the same shape whichever feed it came from.

{ "data": [ { "amassId": "AMBC_RwzeOtqYiRA2S523v1jL81OgndQ", "pmid": "34626851", "pmcid": "PMC8859548", "doi": "10.1016/j.molmet.2021.101351", "title": "GLP-1 physiology informs the pharmacotherapy of obesity", "abstract": "BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP1RA) augment glucose-dependent insulin release and reduce glucagon secretion and gastric emptying, enabling their successful development for the treatment of type 2 diabetes (T2D).…", "authors": ["Daniel J. Drucker"], "journal": "Molecular metabolism", "issn": "2212-8778", "volumeIssue": "57", "language": "eng", "publicationDate": "2022-03-01", "publicationTypes": ["Journal Article", "Research Support, Non-U.S. Gov't", "Review"], "isRetracted": false, "citationCount": 423, "journalQualityJufo": 2, "meshTerms": ["Adolescent", "Animals", "Diabetes Mellitus, Type 2", "Glucagon-Like Peptide 1", "Glucagon-Like Peptide-1 Receptor", …], "keywords": ["Brain", "Diabetes", "G protein-coupled receptor", "Hunger", "Obesity", …], "substances": ["Glucagon-Like Peptide-1 Receptor", "Liraglutide", "Glucagon-Like Peptide 1"], "hasFulltext": false, "authorsMetadata": [ { "name": "Daniel J. Drucker", "orcid": "0000-0001-6688-8127", "affiliations": [{ "name": "Lunenfeld-Tanenbaum Research Institute", "ror": "01s5axj25", "countryCode": "CA" }] } ], "meshIds": ["D000293", "D000818", "D003924", "D052216", "D000067757", …], "substanceIds": ["D000067757", "D000069450", "D052216"], "referencesTrialCore": [], "references": ["AMBC_5km7Q541cJN5a8RcTUN2tcgYoRj", "AMBC_WUubCFjk6wfURImFXwtDEvKquIE", "AMBC_3pwzL1urfguQm7s2L8Jlj04onOR", "AMBC_YDNDzsaB3vLPfxW6MNxdJU7vwI0", "AMBC_KH7wBl2Araj9gbLXuQWOHefvkIs", …], "citedBy": ["AMBC_B5CfpHBkdFha6MX0Q2GJpCBMw3o", "AMBC_UAflDqTKZtUAEny8XTtIvPvCWu7", "AMBC_P2sn7qrFvXfd8grl0s5scQ2El3t", "AMBC_5Er4ez0MRO1LsHzGpqflcUlzSFZ", "AMBC_PB5LfnIhIOOXiZLcXAokubVODU8", …] }, { "pmid": "32987188", "title": "Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease", "citationCount": 270, … }, { "pmid": "35907261", "title": "Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease", "citationCount": 113, … }, { "pmid": "41654015", "title": "Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues", "citationCount": 0, … }, { "pmid": "29317623", "title": "GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose", "citationCount": 181, … } ] }

From literature to label.In one API.

From literature to label.In one API.

From literature to label.
In one API.

From literature to label.
In one API.